16 research outputs found
Exploring Methods to Persuade Users to watch Social Problem Films through the Case Study of Race-related Films
The present study reports on the success of persuasive techniques and recommendation engine on persuading participants to choose a race-related movie. The study used a technical component as well as an experimental study to see how users respond to certain persuasive techniques. The technical component included a content-based filtering recommendation engine to recommend lists of movies to participants based on films they already enjoy. Persuasive techniques were then applied to those lists and results were measured and analyzed. This project aims to explore the relationship that recommendation engines and persuasive techniques have on users and their willingness to branch out in the content they consume. This study allowed me to get a baseline for how users respond to certain techniques if this study were to be done on a larger scale
Quantum Monte Carlo with Directed Loops
We introduce the concept of directed loops in stochastic series expansion and
path integral quantum Monte Carlo methods. Using the detailed balance rules for
directed loops, we show that it is possible to smoothly connect generally
applicable simulation schemes (in which it is necessary to include
back-tracking processes in the loop construction) to more restricted loop
algorithms that can be constructed only for a limited range of Hamiltonians
(where back-tracking can be avoided). The "algorithmic discontinuities" between
general and special points (or regions) in parameter space can hence be
eliminated. As a specific example, we consider the anisotropic S=1/2 Heisenberg
antiferromagnet in an external magnetic field. We show that directed loop
simulations are very efficient for the full range of magnetic fields (zero to
the saturation point) and anisotropies. In particular for weak fields and
anisotropies, the autocorrelations are significantly reduced relative to those
of previous approaches. The back-tracking probability vanishes continuously as
the isotropic Heisenberg point is approached. For the XY-model, we show that
back-tracking can be avoided for all fields extending up to the saturation
field. The method is hence particularly efficient in this case. We use directed
loop simulations to study the magnetization process in the 2D Heisenberg model
at very low temperatures. For LxL lattices with L up to 64, we utilize the
step-structure in the magnetization curve to extract gaps between different
spin sectors. Finite-size scaling of the gaps gives an accurate estimate of the
transverse susceptibility in the thermodynamic limit: chi_perp = 0.0659 +-
0.0002.Comment: v2: Revised and expanded discussion of detailed balance, error in
algorithmic phase diagram corrected, to appear in Phys. Rev.
Disequilibrium Carbon, Oxygen, and Nitrogen Chemistry in the Atmospheres of HD 189733b and HD 209458b
We have developed 1-D photochemical and thermochemical kinetics and diffusion
models for the transiting exoplanets HD 189733b and HD 209458b to study the
effects of disequilibrium chemistry on the atmospheric composition of "hot
Jupiters." Here we investigate the coupled chemistry of neutral carbon,
hydrogen, oxygen, and nitrogen species, and we compare the model results with
existing transit and eclipse observations. We find that the vertical profiles
of molecular constituents are significantly affected by transport-induced
quenching and photochemistry, particularly on cooler HD 189733b; however, the
warmer stratospheric temperatures on HD 209458b can help maintain
thermochemical equilibrium and reduce the effects of disequilibrium chemistry.
For both planets, the methane and ammonia mole fractions are found to be
enhanced over their equilibrium values at pressures of a few bar to less than a
mbar due to transport-induced quenching, but CH4 and NH3 are photochemically
removed at higher altitudes. Atomic species, unsaturated hydrocarbons
(particularly C2H2), some nitriles (particularly HCN), and radicals like OH,
CH3, and NH2 are enhanced overequilibrium predictions because of quenching and
photochemistry. In contrast, CO, H2O, N2, and CO2 more closely follow their
equilibrium profiles, except at pressures < 1 microbar, where CO, H2O, and N2
are photochemically destroyed and CO2 is produced before its eventual
high-altitude destruction. The enhanced abundances of HCN, CH4, and NH3 in
particular are expected to affect the spectral signatures and thermal profiles
HD 189733b and other, relatively cool, close-in transiting exoplanets. We
examine the sensitivity of our results to the assumed temperature structure and
eddy diffusion coefficientss and discuss further observational consequences of
these models.Comment: 40 pages, 16 figures, accepted for publication in Astrophysical
Journa
Therapy with un-engineered naĂŻve rat umbilical cord matrix stem cells markedly inhibits growth of murine lung adenocarcinoma
<p>Abstract</p> <p>Background</p> <p>Lung cancer remains the leading cause of cancer-related mortality despite continuous efforts to find effective treatments. Data from the American Cancer Society indicate that while the overall incidence of lung cancer is declining, it continues to rise in women. Stem cell-based therapy has been an emerging strategy to treat various diseases. The purpose of this paper is to determine the efficacy of an intrinsic anti-cancer effect of rat umbilical cord matrix stem cells (UCMSCs) on lung cancer.</p> <p>Methods</p> <p>A mouse syngeneic lung carcinoma model was used to test the basic ability of UCMSCs to control the growth of lung cancer. Lung tumors were experimentally induced by tail vein administration of Lewis lung carcinoma (LLC) cells derived from the lung of C57BL/6 mouse. Rat UCMSCs were then administered intratracheally five days later or intravenously on days 5 and 7. The tumor burdens were determined by measuring lung weight three weeks after the treatment.</p> <p>Results</p> <p>Co-culture of rat UCMSCs with LLC significantly attenuated the proliferation of LLC cells as monitored by MTT (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), a tetrazole cell proliferation assay, thymidine uptake, and direct cell counts. <it>In vitro </it>colony assays with rat UCMSCs as feeder layers markedly reduced LLC colony size and number. Co-culture of rat UCMSCs with LLCs causes G0/G1 arrest of cancer cells. This is evident in the decrease of cyclin A and CDK2 expression. The <it>in vivo </it>studies showed that rat UCMSC treatment significantly decreased tumor weight and the total tumor mass. Histological study revealed that intratracheally or systemically administered rat UCMSCs homed to tumor areas and survived for at least 3 weeks without any evidence of differentiation or adverse effects.</p> <p>Conclusions</p> <p>These results indicate that rat UCMSCs alone remarkably attenuate the growth of lung carcinoma cells <it>in vitro </it>and in a mouse syngeneic lung carcinoma graft model and could be used for targeted cytotherapy for lung cancer.</p